定量构效关系用于金属纳米材料毒性预测的研究进展

Journal: Ecological Environment and Protection DOI: 10.32629/eep.v9i8.3301

胡璐豪, 马旭

重庆三峡科技大学 环境与化学工程学院

Abstract

随着金属纳米材料的广泛应用,其环境风险备受关注。定量纳米结构活性关系(QNAR )模型为高效预测其毒性提供了新途径。本文阐述了金属纳米材料毒性机制与影响因 素;探讨了包括特征描述符筛选与算法应用在内的QNAR模型构建方法;最后指出QN AR研究今后努力的方向。

Keywords

定量构效关系;金属纳米材料;定量纳米结构活性关系;纳米毒理学

Funding

重庆市教委科学技术研究项目(溶解性有机质作用下纳米硫化汞的化学生成机制研究K JQN202101209,天然有机质增强纳米硫化汞溶解机制研究KJQN202201230)资助。

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