CYP79D16介导的长柄扁桃苦杏仁苷合成调控与生态-医药协同开发研究
Journal: Agricultural Science DOI: 10.12238/as.v8i4.2877
Abstract
长柄扁桃(Prunus pedunculat Pall.)是一种兼具生态修复与药用价值的沙生油料灌木。本研究通过整合生物信息学分析与生态适应性评估,系统解析了CYP79D16基因在苦杏仁苷(Amygdalin)生物合成中的关键调控作用及其进化机制。研究显示,CYP79D16基因底物结合域的高度保守性维持了苦杏仁苷合成的核心催化活性。此外,CYP79D16野生种群的等位变异为选育高含量、稳定型品种提供了遗传资源。研究进一步提出生态-医药协同开发策略：通过基因编辑或跨物种合成生物学手段构建高效氰苷合成体系,同时结合荒漠化修复需求选育抗旱高苷品系。本研究为长柄扁桃的资源开发与苦杏仁苷产业化应用提供了理论依据,并为沙生植物的多功能利用提供了范例。
Keywords
长柄扁桃；苦杏仁苷；CYP79D16基因；医药开发
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