Diagnostic Value of Holter Monitoring QT Interval Combined with Treadmill Exercise Test for Multivessel Coronary Artery Disease in Patients with Coronary Heart Disease
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v7i2.5317
Abstract
Objective: To investigate the diagnostic value of Holter monitoring QT interval combined with treadmill exercise test (TET) in patients with multivessel coronary artery disease in coronary heart disease. Methods: A total of 230 patients with coronary artery disease treated at our hospital between July 2023 and December 2024 were enrolled. Patients were grouped based on coronary angiography results as the gold standard: 100 cases in the multivessel disease group and 130 cases in the non-multivessel disease group. We compared QT interval and TET-related indicators between the two groups and analyzed the diagnostic efficacy of single QT interval detection, single TET detection, and combined detection for detecting multivessel coronary artery disease. Results: Both QT interval and TET-related indicators were significantly higher in the multivessel group than in the non-multivessel group (P<0.05). The diagnostic performance metrics (sensitivity, specificity, accuracy) of combined detection significantly outperformed single-method detection (P<0.05). Conclusion: Combining Holter ECG QT interval monitoring with exercise stress testing (EST) significantly enhances diagnostic efficacy for multi-vessel coronary artery disease in CHD patients. This noninvasive, convenient approach warrants clinical implementation.
Keywords
Holter monitoring; QT interval; exercise stress test; coronary heart disease; multivessel coronary artery disease
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[9]Zhang Fan, Zheng Linjun, Bao Yanping. Predictive Efficacy of Exercise Treadmill Test Combined with Holter Monitoring for Post-PCI Ischemia in Coronary Heart Disease Patients [J]. Electrocardiography and Circulation, 2025, 44(04): 435-439.
[10]Ren Jing'er, Wang Zhibin, Chen Li. Clinical Value Analysis of Holter Monitoring QTc Interval Combined with Exercise Treadmill Test in Diagnosing the Number of Coronary Artery Lesions in Coronary Heart Disease [J]. Journal of Medical Forum, 2025, 46(20): 2150-2154.
[11]Guo Yanfeng, Niu Shuangshuang. Clinical Significance of Holter Monitoring Combined with Treadmill Exercise Test in Diagnosing Myocardial Ischemia in Coronary Heart Disease [J]. Chinese School Physician, 2025, 39(02): 151-153.
[12]Ren Jing'er, Zhang Yuanyuan. Application of Treadmill Exercise Test Combined with 12-Lead Holter Monitoring in Diagnosing Myocardial Ischemia in Coronary Heart Disease [J]. Journal of Henan Medical College, 2025, 37(04): 429-431.
[2]B. E M,A. B R,S. A S, et al. Radiomorphological changes of the coronary artery in patients with coronary artery disease with recurrent angina in the first year after angioplasty and stenting of multi-vessel lesions[J].Cardiovascular Therapy and Prevention,2019,18(5):10-16.
[3]Li Zhiming. A Study on the Diagnostic Effectiveness of Siemens 64-Slice 128-Layer Spiral CT Coronary Imaging Technology and Coronary Angiography in Visualizing Coronary Stenotic Lesions in Patients with Coronary Heart Disease [J]. World Latest Medical Information Abstract, 2019, 19(54): 154+156.
[4]Pan Yaqiong, Zhang Zhi, Cheng Hai, et al. Correlation Analysis and Clinical Significance of Holter ECG Parameters and Serum Syndecan-4 Levels with Coronary Artery Disease Severity in Patients with Coronary Heart Disease [J]. Medical Theory and Practice, 2024, 37(20): 3440-3443.
[5]Xue Yanxia. Predictive Value of Exercise Treadmill Test Combined with Holter Monitoring and Echocardiography for Assessing Coronary Artery Disease Severity in Asymptomatic Patients with Myocardial Ischemia [J]. E-Journal of Cardiovascular Diseases in Chinese and Western Medicine, 2019, 7(04):193.
[6]Lu Yige, He Wei, Lin Hongyan, et al. Diagnosis of Myocardial Ischemia in Coronary Heart Disease Using CT Pericoronary Fat Attenuation Combined with Machine Learning Algorithms [J]. Chinese Journal of Arteriosclerosis, 2024, 32(06):514-520.
[7]Li Yanli, Sun Jing, Chen Yan, et al. Value of Holter Monitoring Combined with Clinical Pathways in Evaluating Coronary Heart Disease with Arrhythmia [J]. Imaging Science and Photochemistry, 2022, 40(02): 316-319.
[8]Xu Guifen, Ke Zunmiao, Chen Lifang, et al. Diagnostic Value of Pre-test Probability Combined with Electrocardiogram Exercise Treadmill Test in Suspected Stable Coronary Atherosclerotic Heart Disease [J]. Chinese Journal of Hypertension, 2022, 30(04): 359-363.
[9]Zhang Fan, Zheng Linjun, Bao Yanping. Predictive Efficacy of Exercise Treadmill Test Combined with Holter Monitoring for Post-PCI Ischemia in Coronary Heart Disease Patients [J]. Electrocardiography and Circulation, 2025, 44(04): 435-439.
[10]Ren Jing'er, Wang Zhibin, Chen Li. Clinical Value Analysis of Holter Monitoring QTc Interval Combined with Exercise Treadmill Test in Diagnosing the Number of Coronary Artery Lesions in Coronary Heart Disease [J]. Journal of Medical Forum, 2025, 46(20): 2150-2154.
[11]Guo Yanfeng, Niu Shuangshuang. Clinical Significance of Holter Monitoring Combined with Treadmill Exercise Test in Diagnosing Myocardial Ischemia in Coronary Heart Disease [J]. Chinese School Physician, 2025, 39(02): 151-153.
[12]Ren Jing'er, Zhang Yuanyuan. Application of Treadmill Exercise Test Combined with 12-Lead Holter Monitoring in Diagnosing Myocardial Ischemia in Coronary Heart Disease [J]. Journal of Henan Medical College, 2025, 37(04): 429-431.
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