Type IIIa Esophageal Atresia, Duodenal Atresia, and Intestinal Atresia in One of the Monochorionic, Diamniotic Twins: A Multi-Surgery Approach for Treatment
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v6i2.3895
Abstract
One of the monochorionic, diamniotic twins combined with type IIIa esophageal atresia, duodenal atresia, and intestinal atresia pose a rare management challenge. A female neonate from a monochorionic, diamniotic twin pregnancy who was diagnosed with multiple congenital malformations, including long-segment esophageal atresia with duodenal atresia, and intestinal atresia. These malformations were partially detected during prenatal ultrasound and were treated with a series of surgeries after birth. However, the patient continues to experience persistent esophageal stenosis, requiring regular dilation treatment. The treatment of multiple gastrointestinal malformations remains a significant challenge and may require multiple surgeries. Potential causes of defects and phenotypic differences in monozygotic twins, including genetic mutations, epigenetic factors, and non-genetic factors such as differences in amniotic sac size, uneven blood supply, and placental dysfunction. The probability of multiple digestive tract atresia occurring in one of the monozygotic twins is extremely low, and the reasons are diverse, requiring multiple surgeries.
Keywords
Esophageal Atresia, Duodenal Atresia, Intestinal Atresia, Twin
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Copyright © 2025 Cheng Tian, Jingsi Liu, Zhen Yang, Xianglun Sun, Ban Li, Kanglin Dai
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