Journal: Frontier Forum of Clinical Medicine DOI: 10.32629/ffcr.v3i10.21295
Abstract
石墨烯及其衍生物因其独特的二维结构、优异的力学性能、高比表面积和可调控的表面化学性质，在生物医学领域展现出巨大的应用潜力。其具有抗菌、加速皮肤伤口愈合、促进成骨、神经再生、血管生成等作用。其中，血管生成作为多种病理修复过程的关键生物学事件，已成为生物医学领域的研究热点。本文主要对近年来石墨烯及其衍生物在血管生成领域的研究进展作简要综述，探讨了其在内皮细胞行为调控、血管生成因子表达、免疫微环境调节等方面的作用，并分析了相关分子机制。同时，讨论石墨烯材料的生物安全性问题及其在临床转化中面临的挑战，对其未来发展前景进行了展望。
Keywords
石墨烯及其衍生物；血管生成；血管化；组织修复；组织工程
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