Patients who tested positive for COVID-19 by rapid test and their oral clinical characteristics
Journal: Advances in Medicine and Engineering Interdisciplinary Research DOI: 10.32629/ameir.v4i1.4895
Abstract
Introduction: The pandemic caused by SARS-CoV-2 infection is associated with variable oral clinical manifestations, ranging from mild or almost nonexistent symptoms to fatal complications.
Objective: To describe the oral clinical manifestations in patients with a positive rapid test for COVID-19.
Methods: An observational, descriptive, and cross-sectional study was conducted on 54 patients with a positive rapid test for COVID-19 who presented with oral clinical manifestations. These patients were treated at the Emergency Respiratory Diseases Service of the José Martí Teaching Polyclinic in Santiago de Cuba from January to August 2021. Variables analyzed included the presence or absence of symptoms, their type, location, and time of onset. Absolute and relative frequencies were used as summary measures.
Results: Symptomatic patients predominated in the series (75.9%); diffuse erythema was the most frequent lesion (14.8%), and xerostomia was the only manifestation among asymptomatic patients. It is worth noting that most oral clinical manifestations were present before the onset of general symptoms (63.4%).
Conclusions: Oral clinical manifestations were confirmed in patients with a positive rapid test for COVID-19.
Keywords
covid-19; test of quick diagnosis; oral clinical manifestations
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[16] Santos Velázquez T, Aciet Cruz L. Manifestaciones bucales en pacientes con COVID-19 atendidos en un centro de aislamiento en Las Tunas. Rev. electrón. Dr. Zoilo E. Marinello Vidaurreta. 2021 [citado 26/03/2023];46(3). Disponible en: https://revzoilomarinello.sld.cu/index.php/zmv/article/view/2808
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Disponible en:https://pubmed.ncbi.nlm.nih.gov/32564416/
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[19] Xu H, Zhong L, Deng J, Peng J, Dan H, Zeng X, et al. High expression of ACE2 receptor of 2019-nCoVon the epithelial cells of oral mucosa. Int J Oral Sci. 2020 [citado 26/03/2023];12(1):
Disponible en: https://www.nature.com/articles/s41368-020- 0074-x
[2] Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 [citado 25/03/2023]; 382(18).
Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092819/
[3] Cuba. Sitio Oficial de Gobierno del Ministerio de Salud Pública. COVID-19. Parte de cierre del 25 de marzo de 2023 [citado 26/12/2023]. Disponible en: https://salud.msp.gob.cu/2023/03/25/
[4] Chile. Ministerio de Salud. Orientaciones para la atención odontológica en fase IV de COVID-19. Santiago de Chile: Subsecretaría de Salud Pública División de Prevención y Control de Enfermedades, 2020 [citado 26/03/2023].
Disponible en:
https://diprece.minsal.cl/wp-content/uploads/2020/03/ORIENTACIONES- ATENCION-ODONTOLOGICAS-COVID-19-.pdf
[5] Tang YW, Schmitz J, Persing D, Stratton Ch. Laboratory Diagnosis of COVID-19 Infection: Current Issues and Challenges. J Clin Microbiol. 2020 [citado 26/03/2023]; 58(6).
Disponible en:https://journals.asm.org/doi/10.1128/jcm.00512-20
[6] Galván Casas C, Catalá A, Carretero Hernández G, Rodríguez Jiménez P, Fernández Nieto D, Rodríguez Villa LA, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020 [citado 26/03/2023]; 183(1):71-7.
Disponible en: https://pubmed.ncbi.nlm.nih.gov/32348545/
[7] Amorim Dos Santos J, Normando AGC, Carvalho da Silva RL, De Paula RM, Cembranel AC, Santos Silva AR, et al. Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations? Int J Infect Dis. 2020
[citado 26/03/2023]; 97:326- 8.
Disponible en: https://www.sciencedirect.com/science/article/pii/S1201971220304471?via%3Dih ub
[8] Cornejo Ovalle M, Espinoza Santander I. COVID-19 y manifestaciones orales. Int J Odontostomat. 2020 [citado 26/03/2023];14(4):538-9. Disponible en:
https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718- 381X2020000400538&lng=en&nrm=iso&tlng=en
[9] Muñoz Álvarez Y, Chávez Taset I, Alarcón Chávez L, Roselló Salcedo O, Quesada Torres Y. Manifestaciones bucales por infección de COVID-19 en trabajadores de la Clínica Estomatológica de Campechuela. Rev. electrón. Dr. Zoilo E. Marinello Vidaurreta. 2022 [citado 26/03/2023]; 47(2).
Disponible en: https://revzoilomarinello.sld.cu/index.php/zmv/article/view/3016
[10] Jiménez Cauhe J, Ortega Quijano D, Carretero Barrio I, Suarez Valle A, Saceda Corralo D, Moreno García del Real C, et al. Erythema multiforme-like eruption in patients with COVID-19 infection: clinical and histological findings. Clin Exp Dermatol. 2020 [citado 26/03/2023]; 45(7). Disponible en: https://doi.org/10.1111/ced.14281
[11] Iranmanesh B, Khalili M, Amiri R, Zartab H, Aflatoonian M. Oral manifestations of COVID-19 disease: A review article. Dermatol Ther. 2021 [citado 26/03/2023]; 34(1): e14578.
Disponible en:https://pubmed.ncbi.nlm.nih.gov/33236823/
[12] Pino Román IM, Gómez Cuba D, Álvarez Martínez OL. Manifestaciones bucales en paciente con COVID-19. Informe de caso. Acta médica del centro. 2021 [citado 26/03/2023]; 15(3): 450-456.
Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2709-79272021000300450&lng=es
[13] Parra Sanabria EA, Bermúdez Bermúdez M, Peña Vega CP, Rueda Jiménez A. Manifestaciones orales y maxilofaciales asociadas a la COVID-19. Revisión de la literatura. Acta Odontol Colomb. 2020 [citado 26/03/2023];10 (Supl.COVID–19). Disponible en: https://revistas.unal.edu.co/index.php/actaodontocol/article/view/89447/77506
[14] Calero F, Quispe Vargas R, La Serna Ojeda C, Floreano Calero ML, Mattos A. Manifestaciones orales en pacientes con COVID-19. KIRU. 2020 [citado 26/03/2023]; 18(3): 194-202. Disponible en: https://www.researchgate.net/publication/355109144_Manifestaciones_orales_en_p acientes_con_COVID-19
[15] Capocasale G, Nocini R, Faccioni P, Donadello D, Bertossi D, Albanese M, et al. How to deal with coronavirus disease 2019: A comprehensive narrative review about oral involvement of the disease. Clin Exp Dent Res. 2021 [citado 26/03/2023]; 7(1):101-8. Disponible en:https://pubmed.ncbi.nlm.nih.gov/33021087/
[16] Santos Velázquez T, Aciet Cruz L. Manifestaciones bucales en pacientes con COVID-19 atendidos en un centro de aislamiento en Las Tunas. Rev. electrón. Dr. Zoilo E. Marinello Vidaurreta. 2021 [citado 26/03/2023];46(3). Disponible en: https://revzoilomarinello.sld.cu/index.php/zmv/article/view/2808
[17] da Silva Pedrosa M, Sipert CR, Nogueira FN. Altered taste in patients with COVID-19: The potential role of salivary glands. Oral Dis. 2021 [citado 26/03/2023]; 27(Suppl 3):798-800.
Disponible en:https://pubmed.ncbi.nlm.nih.gov/32564416/
[18] Brann D, Tsukahara T, Weinreb C, Lipovsek M, Van den Berge K, Gong B, et al. Non- neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia. Sci Adv. 2020 [citado 26/03/2023];6(31). Disponible en:https://pubmed.ncbi.nlm.nih.gov/32937591/
[19] Xu H, Zhong L, Deng J, Peng J, Dan H, Zeng X, et al. High expression of ACE2 receptor of 2019-nCoVon the epithelial cells of oral mucosa. Int J Oral Sci. 2020 [citado 26/03/2023];12(1):
Disponible en: https://www.nature.com/articles/s41368-020- 0074-x
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