黄芪在肿瘤治疗中的研究进展
Journal: Frontiers of Chinese Medicine Research DOI: 10.12238/fcmr.v7i1.12524
Abstract
黄芪作为常用大宗中药,在《神农本草经》中早有记载。其来源为豆科植物蒙古黄或膜荚黄芪的干燥根。黄芪富含多糖、黄酮、皂苷等成分,其中黄芪多糖(APS)是关键活性成分。现代研究表明,黄芪及其活性成分在抗肿瘤方面表现突出。APS能通过多途径发挥抗肿瘤作用,如直接抑制肿瘤细胞增殖与转移,调节肿瘤免疫微环境,还可协同放化疗及免疫治疗,减轻化疗副作用并增强免疫治疗效果。临床前动物实验证实其有效性,临床试验也显示黄芪提取物联合化疗可改善患者状况,但仍需大样本研究。未来需深入研究机制,加强临床转化,助力中医药在肿瘤治疗中发挥更大作用。
Keywords
黄芪；肿瘤治疗；组学研究
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