Quantitative Morphological Comparison of Microglia in Normal and Alzheimer's Disease Model Brains
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v6i3.4437
Abstract
The aim of this study is to investigate the potential role of microglia in nervous system function by comparing the morphological characteristics of microglia under physiological and pathological conditions. By reviewing the literature in recent years, this study summarizes the distribution, quantity and morphological changes of microglia under different pathological conditions and analyzes their relationship with functional regulation. The results showed that microglia showed significant morphological plasticity in the activated state, suggesting that they were involved in inflammatory response and neural regulation mechanism.
Keywords
alzheimer's disease, microglia,neurodegenerative disease
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