Development and Bioactivity Evaluation of a “Medicine and Food Homology” Composite Schisandra Chinensis Functional Beverage
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v6i3.4418
Abstract
Schisandra chinensis, a “medicine and food homology” herb, is highly regarded for its medicinal and nutritional value. Composite beverages that combine Schisandra chinensis with other medicinal and edible plants are gaining popularity due to their traditional health benefits. The orthogonal experiment results showed that the optimal formulation consisted of 30% Composite Schisandra chinensis extract (Schisandra chinensis: Lycium barbarum: Ophiopogon japonicus=4:1:1), 8% xylitol, and 0.010% citric acid. In vivo studies that all dose groups reduced malondialdehyde (MDA) and hydrogen peroxide (H2O2) levels to varying degrees (P<0. 05), mitigating the oxidative damage induced by alcohol consumption. The anti-fatigue effect was more pronounced with higher concentrations of the Composite Schisandra chinensis beverage extract (P<0. 05). No significant toxic side effects were observed in the beverage formulated with xylitol and citric acid as excipients. Additionally, all dosage groups significantly increased ear swelling difference (P<0. 05) and modulated cyclophosphamide-induced organ index alterations in varying extents (P<0. 05), indicating enhanced immune function in the experimental animals.
Keywords
medicine and food homology; composite Schisandra chinensis beverage; antioxidant activity; anti-fatigue effects; acute toxicity; immune enhancement
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Copyright © 2025 Da Li, Feng Ye, Jian Xu, Jing Zhang, Shuting Lu
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