Progress in Early Nutritional Support in Acute Pancreatitis
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v5i4.3286
Abstract
Acute pancreatitis (acute pancreatitis, AP) is an inflammatory reaction caused by cholelithiasis, alcohol, tumor and other factors of pancreatic enzymes, which causes digestion, edema, bleeding and even necrosis. Usually characterized by acute epigastric pain, nausea, vomiting, fever and elevated hematuria amylase, and low back pain, severe patients may experience shock, even multiple organ failure and death. Nowadays, in clinical work, AP patients are usually treated with fasting water, but there is no clear indicator on when and how to open the diet. At present, according to domestic and foreign guidelines and relevant literature, the following can be clearly indicated. ① AP patients should resume solid diet as soon as possible according to their actual tolerance, so as to minimize the risk of infection and death. ② If the patient's oral energy cannot meet their own needs, enteral feeding should be started as soon as possible within 24 to 72 h. ③ TPN/NPO is only indicated for patients with contraindications to enteral nutrition, such as persistent paralytic ileus.
Keywords
Acute pancreatitis, Early nutritional support, Clinical
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[3] Chowdhury AR, Chang P, Zhou S, et al. Optimal initial diet in mild acute pancreatitis: A comprehensive meta-analysis of randomized control trials. Pancreatology. 2022;22(7):858-863.
[4]Tenner S, Baillie J, DeWitt J, Vege SS; American College of Gastroenterology. American College of Gastroenterology guideline: management of acute pancreatitis. Am J Gastroenterol. 2013;108(9):1400-15; 1416.
[5]Tenner S, Vege SS, Sheth SG, et al. American College of Gastroenterology Guidelines: Management of Acute Pancreatitis. Am J Gastroenterol. 2024;119(3):419-437.
[6]Emergency Medicine Branch of the Chinese Medical Association, Beijing-Tianjin-Hebei Emergency and Urgent Care Consortium, Emergency Medicine Branch of the Beijing Medical Association, et al. Expert consensus on emergency diagnosis and treatment of acute pancreatitis[J]. Chinese Journal of Emergency Medicine,2021,30(2):161-172.
[7]Zhao XL, Zhu SF, Xue GJ, et al. Early oral refeeding based on hunger in moderate and severe acute pancreatitis: a prospective controlled, randomized clinical trial. Nutrition. 2015;31(1):171-5.
[8]Arvanitakis M, Ockenga J, Bezmarevic M, et al. ESPEN guideline on clinical nutrition in acute and chronic pancreatitis. Clin Nutr 2020; 39(3):612–631.
[9]Crockett SD, Wani S, Gardner TB, et al. American Gastroenterological Association Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on initial management of acute pancreatitis. Gastroenterology 2018; 154(4):1096–1101.
[10]Bakker OJ, van Brunschot S, van Santvoort HC, et al. Early versus on-demand nasoenteric tube feeding in acute pancreatitis. N Engl J Med 2014; 371(21):1983–1993.
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