经皮支气管动脉灌注化疗联合免疫治疗晚期肺癌的回顾性临床观察
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v8i1.18600
Abstract
目的：经皮支气管动脉灌注化疗联合免疫检查点抑制剂治疗肺癌的临床疗效和安全性。方法：回顾性分析2023年10月至2025年7月黄河三门峡医院收治的晚期肺癌患者共9例,所有患者入院后病理证实为肺癌。根据治疗方法将所有组进行分析观察。结果：经皮支气管动脉灌注化疗(BAI)(白蛋白结合型紫杉醇+卡铂)联合免疫检查点抑制剂治疗晚期肺癌患者,显示出一定的抗肿瘤活性(ORR66.6%,DCR90%)和可接受的安全性(以1-2级不良反应为主)。结论：经皮支气管动脉灌注化疗(BAI)联合免疫检查点抑制剂治疗能有效地控制中晚期肺鳞癌,近期疗效明确,抑制肿瘤生长,延长患者的无疾病进展生存期,有延长总生存期的趋势,安全性好。
Keywords
支气管动脉；灌注化疗；肺癌；免疫检查点抑制剂
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