紧张型头痛与焦虑抑郁的关联机制及临床管理进展综述

Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v8i1.18596

李洪燕1, 杨松1, 侯月2, 米珍1

1. 拉萨市人民医院神经内科
2. 首都医科大学宣武医院神经内科

Abstract

紧张型头痛(tension-type headache,TTH)是最常见的原发性头痛,严重影响患者的生活质量和心理健康。TTH患者中焦虑、抑郁的共病现象很常见,两者间存在复杂的双向交互影响机制。本文系统回顾了紧张型头痛与焦虑抑郁的流行病学特征、病理生理机制、临床表现及其彼此间的相互作用,分析了神经炎症、中枢敏化、人格特质与社会心理因素在这些关系中的效应。结合最新的临床研究,评述了合并焦虑抑郁的TTH患者的具体综合治疗策略,包括药物治疗、心理辅导以及非药物的治疗方法。借助对现有文献的分析总结,为临床诊疗提供理论依据与实践操作指引,从而促进TTH患者的整体管理及预后提升。

Keywords

紧张型头痛;焦虑抑郁;共病机制;治疗

Funding

课题基金号:SYKY2023020。

References

[1] SPECIALI J G,ECKELI A L,DACH F. Tension-type headache [J].Expert Rev Neurother,2008,8(5):839-53.
[2] BEGHI E, BUSSONE G, D'AMICO D, et al. Headache, anxiety and depressive disorders: the HADAS study [J]. J Headache Pain, 2010,11(2):141-50.
[3] CHO S J,SONG T J,CHU M K.Sleep and Tension-Type Heada
[4] PORST M,WENGLER A,LEDDIN J,et al.Migraine and tension
[5] JIA Z,WAN D, YIN Z,et al.Depression and anxiety in Chin
[6] MIRZAEVA L M, LOBZINA A S, AKHMEDOVA K N, et al. [Thera
[7] MATTA A P,MOREIRA FILHO P F. [Depressive symptoms and anxiety in patients with chronic and episodic tension-type headache][J].Arquivos de neuro-psiquiatria,2003,61(4):991-4.
[8] LYU Z,GUO Y,GONG Y,et al.The Role of Neuroglial Crosst
[9] SHEN W,ZOU B L,LI D D, et al. [Effect of acupuncture on pain-emotion related brain regions in patients with cervical spondylosis of cervical type: a fMRI study] [J]. Zhongguo zhen jiu=Chinese acupuncture & moxibustion,2021,41(8):906-12.

Copyright © 2026 李洪燕, 杨松, 侯月, 米珍

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License