经皮球囊压迫术治疗三叉神经痛的个体化策略与临床进展
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v8i1.18554
Abstract
目的：总结近5年经皮球囊压迫术(PBC)治疗三叉神经痛(TN)的个体化策略与临床进展,提炼实践要点。方法：检索近5年国内外文献,归纳术前Meckel腔与卵圆孔评估、三维影像/导航或机器人辅助、麻醉与器械改良、压迫参数优化、疗效与复发预测及并发症防控。结果：研究表明,以Meckel腔和卵圆孔形态为基础制定个体化穿刺策略,联合三维影像导航和机器人技术,可显著提高手术成功率和短期镇痛效果；改良器械、清醒/镇静操作及分阶段压迫等方案,有助于在维持较高即时无痛率的同时降低复发和手术相关并发症风险。电生理指标及影像学特征联合临床资料构建的预测模型,可用于评估术后镇痛持续时间及复发概率,为患者分层管理和随访策略制定提供依据。结论：PBC是高龄或不宜开颅TN患者的重要微创个体化治疗选择。在先进影像导航、电生理监测及预测模型的支持下,构建分层化、个体化的决策路径,有望进一步优化疗效—风险平衡,但仍需高质量多中心前瞻性研究加以验证。
Keywords
三叉神经痛；经皮球囊压迫术；个体化治疗；影像引导；复发
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