骨转移微环境中的代谢重编程

Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i5.16508

杨长游, 李兆峰, 秦毅

暨南大学珠海临床医学院

Abstract

癌症骨转移是晚期癌症患者的主要并发症。骨转移微环境是一个独特而复杂的龛位,支持骨中癌细胞和正常细胞的生长和进展。代谢串扰在癌症骨转移的发生和进展中起着至关重要的作用。癌细胞通过改变骨细胞的代谢来促进骨转移。因此,了解癌细胞与骨细胞之间的代谢串扰机制对于开发靶向癌症骨转移的新治疗策略至关重要。

Keywords

骨转移；代谢重编程；骨细胞

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