基于序列信息的血红素配体结合残基识别
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v4i3.5204
Abstract
血红素在生命活动中发挥重要作用,识别血红素结合位点的残基,有助于更好地理解血红蛋白的生物学功能,揭示血红蛋白作用机制,并为蛋白质设计提供有价值信息。本文通过整理Biolip数据库中,血红素配体与蛋白质结合残基及其近邻残基信息,以血红素结合残基和非结合残基的氨基酸信息、亲疏水性、带电性、氨基酸分类等性质作为指标,并利用矩阵打分方法判别血红素结合位点,取得较好结果。
Keywords
蛋白质配体；位点识别；血红素；序列信息
Funding
内蒙古大学生创新创业训练计划项目(S202119127006,
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